Browse All Vancleave MS Above $1M Properties for Sale

Highway 57 Growth Corridor | I-10 Visibility | Medical-Ready Site Located in the heart of the Highway 57 expansion corridor in Vancleave, just off I-10, this site offers immediate access, visibility, and long-term upside in one of the Gulf Coast's fastest-growing north-south corridors. With interstate proximity and partial I-10 visibility, combined with its position across from an established orthopedic center, the property is ideally positioned for medical office, specialty clinic, therapy services, or professional use. As development continues to push north along Highway 57, opportunities like this -- offering scale, accessibility, and corridor positioning -- are becoming increasingly limited. Whether for immediate conversion or future redevelopment, this property is a strategic acquisition in a proven growth path.

6316 Dobson Road, Vancleave

Listing courtesy of Coldwell Banker Alfonso Realty-OS-B/O.

$1,068,440

4147606 MLS

194.22 +/- acres of BEAUTIFUL land in Vancleave , MS., with 1400 +/- front feet on Summerlin Bayou Rd. (Many big beautiful homes on this road) / NOTE: 50 FOOT RD. EASEMENT to be given through this land to provide access to 153.38 +/- acres adjacent on east side . 153.38 acres is also for sale. ** GREAT OPPORTUNITY for Developer to build a subdivision or estate homes !

Summerlin Bayou Road, Vancleave

Listing courtesy of Caryn Hanson Realty.

$1,200,000

4140982 MLS

113.65 acres ( 3 parcels) with approximately 440 feet fronting HWY 57. Located a short distance north of I-10 across the street from the Reserve Golf Course and just north of Quave Rd. ** MDOT is spending 212 M to widen HWY 57 by this land. ** An adjacent 10 acres is also available to purchase.

Hwy 57 Highway, Vancleave

Listing courtesy of Caryn Hanson Realty.

$1,200,000

4138033 MLS

Large high and dry 33-acre commercial property in prime coveted location just feet and seconds from I-10! Also a convenient quick drive to Promenade shopping, groceries, restaurants and downtown Ocean Springs. Ideal parcel for endless possible businesses and other opportunities!

Seaman Road, Vancleave

Listing courtesy of Wise Realty, LLC.

$1,750,000

4133066 MLS

Prime Commercial potential Opportunity in Vancleave! Unlock the potential of this exceptional property located in one of the fastest-growing areas of Vancleave. Nestled between the existing Highway 57 and the upcoming Highway 57, set to be completed in 2027, this site is perfectly positioned for commercial development. Vancleve is poised to become the next up-and-coming city on the Mississippi Gulf Coast, making this an ideal opportunity for savvy investors. With significant development potential in a region seeing increasing demand, now is the time to act before property values escalate. Seller is willing to do creative financing and willing to divide. There is currently 2 structures located on the property. Seller willing to remove if necessary. Don't miss your chance to secure a stake in this thriving community!

10305 Highway 57, Vancleave

Listing courtesy of Strategic Wealth Realty, Inc..

$1,100,000

4089965 MLS

Prime Waterfront Commercial Development Opportunity Highway 57, Ocean Springs/Vancleave, MS. Exceptional 11-acre */- waterfront commercial development site with deep-water frontage on Fort Bayou, just off I 10 along the expanding Highway 57 corridor. Zoned C-1 Commercial, highly visible property combines outstanding highway exposure, waterfront access and existing site improvements in one of the Mississippi Gulf Coast's fastest-growing commercial corridors. The property features deep-water access navigable to the Gulf of Mexico, approx. one acre private island, and largely cleared site ready for development. Highway 57 is being expanded to four lanes, further enhancing accessibility and long-term investments. Surrounded by residential, commercial, and industrial growth, this property presents outstanding possibilities for a variety of commercial mixed-use developments, retail, restaurants, office space, marine-related businesses, seafood operations, multifamily housing, condominiums, hospitality, commercial ventures permitted under C-1 zoning. Live-Work-Play Communities are so hot right now! Call today and start your development plans on this functional waterfront commercial site offering a rare combination of visibility, accessibility, deep-water frontage minutes from I 10, Ocean Springs, Biloxi, and the Mississippi Gulf Coast! *Buyer to verify acreage, dimensions, zoning, utilities, flood zone, bulkhead condition, permitted uses, and all information deemed important to Buyer's intended use. Call today!

8301 Hwy 57, Vancleave

Listing courtesy of Coldwell Banker Smith Home Rltrs-OS.

Start Your Search

Copyright 2026 Mississippi Gulf Coast Multiple Listing Service, Inc. Buyer and/or Buyer's Agent should verify data and evaluate source. This information is furnished by the Mississippi Gulf Coast Multiple Listing Service, Inc. This data is copyrighted and may not be transmitted, retransmitted, copied, framed, repurposed, or altered in any way for any other site, individual and/or purpose without the express written permission of the Mississippi Gulf Coast Multiple Listing Service, Inc. All properties are subject to prior sale, change or withdrawal. Neither the MLS nor the Listing Broker will be held responsible for any typographical errors, misinformation and misprints and shall be held totally harmless. Data displayed is a portion of, and not a complete listing of all listing information published in the Mississippi Gulf Coast Multiple Listing Service, Inc.

Above $1 Million Vancleave Real Estate

Our website features the best real estate search for above $1 million properties available in Vancleave and surrounding areas. It is the only site you will ever need! It is easy-to-use and updated by the official Realtor®’s database every 15 minutes.

You can save searches, and get daily email alerts of new listings, price changes, sold data, and market reports. Our Interactive Map Search allows you to view properties on a map or refine your search by drawing the boundaries around the area you desire.

Curious about what’s happening in your neighborhood? You can create a custom market report to see what’s active, under contract, and sold in your neighborhood!

Considering selling or refinancing your home? Get an INSTANT property valuation now!